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T*
[(pa)20.3(rt)17.8(ic)18(ip)22.3(an)20.3(t)-781.2(w)13.5(as)-772.2(d)12.2(e)0(c)16(e)13.4(as)19.1(ed)-771(o)12.2(r)-778(in)-769(a)-783.3(v)12.2(eg)20.3(et)18(a)13.4(t)0(i)20(v)0(e)-771(s)11(ta)18(te)18(.)]TJ
0 -1.1869 TD
[(Pa)18.1(rt)17.8(ic)23.5(ip)16.8(a)13.4(n)0(t)16.8(s)-292.5(wi)18.1(th)-281.2(d)12.2(i)0(s)15.7(t)0(u)22.3(r)0(b)20.1(a)0(n)20.3(c)0(e)-287.5(i)0(n)-281.2(c)0(o)20.3(n)12.2(sc)19.1(io)16.8(u)12.2(s)11(n)12.2(e)0(s)19.1(s)-297.9(w)13.5(e)0(r)15.8(e)-295.5(e)13.4(v)0(a)20.3(l)0(-)]TJ
0 -1.1923 TD
[(ua)20.3(te)18(d)-193.7(u)0(s)17.9(i)0(n)22.3(g)-193.7(th)22.3(e)-197.9(C)10.2(o)12.2(m)11.4(a)-197.9(R)10.2(ec)21.4(ov)19.1(er)21.3(y)-193.7(S)0(c)18.1(a)0(l)18(e)0(d)20.3(-)13.2(R)10.2(e)0(v)20.3(i)0(s)15.6(e)13.4(d)]TJ
7.8454 0 0 6.9729 255.0613 191.2252 Tm
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(21)Tj
10.4607 0 0 10.4607 264.8125 186.5763 Tm
0 Tc
[(to)-183.7(d)12.2(e)0(t)18(e)0(r)21.3(-)]TJ
-19.6027 -1.1923 TD
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[(m)-18.9(i)-2.9(n)-6.7(e)-309(w)-18.9(h)1.4(e)-18.9(t)-.9(h)-6.7(e)-18.9(r)-301.1(t)-18.9(he)-18.9(y)-296.7(w)-18.9(ere)-309(i)-18.9(n)-300.1(a)-309(v)-6.7(e)-18.9(ge)-18.9(ta)-18.9(ti)-18.9(ve)-309(s)-7.9(t)-18.9(at)-18.9(e.)]TJ
1.0514 -1.1869 TD
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[(As)-482.2(d)-4.1(i)-.9(scus)-5.3(sed)-481(b)1.4(y)-481(W)-1.5(il)-16.3(s)10.2(o)1.4(n)-481(a)-2.9(n)-4.1(d)-481(co)-4.1(lleagues)-482.2(\()-3.1(19)-4.1(98\),)]TJ
7.8454 0 0 6.9729 277.0015 166.3369 Tm
0 Tc
(2)Tj
10.4607 0 0 10.4607 286.3558 161.6882 Tm
-.0166 Tc
(the)Tj
-21.6622 -1.1923 TD
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[(GOSE)-289.5(can)-289.7(be)-293.9(administered)-289.7(either)-288.7(t)-14.7(o)-279.7(include)-288.5(e)-1.3(ffe)4.2(cts)-290.9(o)-2.5(f)-288.7(p)-2.5(e)4.2(-)]TJ
T*
-.0143 Tc
[(ripher)4.4(al)-221.1(injur)4.4(i)1.1(es)-220(a)4.6(n)-2.1(d)-218.9(o)3.4(ther)-217.8(co)]TJ
11.0669 0 TD
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[(nseq)4.1(uen)4.1(ces)-213.9(of)-217.1(th)4.1(e)-217(i)1.8(nju)4.1(r)-.4(y)-212.7(i)-13.6(n)-202.7(a)-.2(d)4.1(-)]TJ
-11.0669 -1.1869 TD
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[(dition)-284.7(t).3(o)-279.3(t).3(he)-283.5(effects)-280.5(o)-2.9(f)-278.3(t).3(he)-278.1(TBI)-278.3(\(referred)-279.3(to)-279.3(here)-283.5(as)-280.5(GOSE-)]TJ
0 -1.1923 TD
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[(All\))-444.8(or)-444.8(by)-440.4(par)5.1(s)-2.6(in)4.1(g)-445.8(t)1.8(he)-444.6(ef)5.1(fects)-447(o)4.1(f)-444.8(t)1.8(he)-444.6(TBI)-444.8(o)4.1(nly)-445.8(\()5.1(GOSE)4.2(-)]TJ
T*
[(TBI\))5.1(.)]TJ
7.8454 0 0 6.9729 81.9779 104.0314 Tm
-.0231 Tc
(22)Tj
10.4607 0 0 10.4607 95.0173 99.3826 Tm
-.0144 Tc
[(In)-527.9(either)-532.3(c)4.4(a)-1(se,)-528.6(t)1(he)-526.7(rating)-527.9(r)-1.2(eec)4.5(t)-14.4(s)-519(c)4.5(h)-2.2(ange)-532.1(fr)4.3(om)]TJ
-3.371 -1.1869 TD
-.015 Tc
[(pre-injury)-430.9(status.)-437(I)3.7(nitially,)-437(T)2.8(R)-4.8(A)3.9(CK-TBI)-435.3(considered)-436.3(onl)-15(y)]TJ
0 -1.1923 TD
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[(the)-261(e)4.6(ffe)4.6(cts)-258(o)-2.1(f)-255.8(t)1.1(he)-255.6(TBI)-261.2(i)1.1(n)-256.8(t)1.1(he)-261(GOSE)-256.6(ra)4.6(ti)-14.3(n)13.4(g)3.4(s.)-257.5(A)4.6(p)-2.1(proximately)]TJ
T*
-.0152 Tc
[(9)-398.6(m)-3.8(ont)-15.2(h)12.5(s)-399.8(into)-398.6(data)-397.4(collection,)-399.3(the)-402.8(p)2.5(rotocol)-400.8(w)3.7(as)-399.8(changed)]TJ
0 -1.1869 TD
-.016 Tc
[(an)-3.8(d)-827.5(b)-3.8(oth)-833(r)2.7(atin)-3.8(gsGOSE)-3.6(-)-2.8(All)-835.2(a)-2.6(nd)-833(GOSE)-3.6(-T)-3.6(BIwere)]TJ
24.0035 64.2875 TD
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[(obta)4.7(i)-14.2(n)13.5(ed)-408.4(at)-410.7(ea)4.6(ch)-408.4(assessment.)-409.1(In)-408.4(ea)4.6(ch)-413.9(sec)4.7(t)1.2(i)-14.2(o)13.5(n,)-414.6(e)4.6(x)-2(ce)4.6(pt)-410.7(f)4.5(o)-2(r)]TJ
0 -1.1869 TD
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[(that)-238.8(as)-4.8(sessing)-236.6(level)-233.4(o)-3.6(f)-235.6(c)-2.4(onsciousness)-4.8(,)-237.3(t)-.4(he)-235.4(ass)-4.8(e)-2.4(ssor)-241()-.3(rs)-4.8(t)-233.4(q)-3.6(ue-)]TJ
0 -1.1923 TD
-.0149 Tc
[(ri)-14.9(e)14(d)-365.8(the)-364.6(l).5(evel)-362.6(of)-364.8(functional)-362.6(limit)-14.9(a)14(tion)-365.8(a)3.9(ssociated)-365.8(w)4(ith)-365.8(the)]TJ
T*
-.0147 Tc
[(ove)4.2(r)-1.5(all)-470.8(i).7(njury)-474(a)4.1(nd)-474(then)-468.5(asked)-468.5(t)-14.7(h)13(e)-472.8(int)-14.7(e)14.2(rviewee)-472.8(to)-474(a)4.2(s)-3.7(sess)]TJ
0 -1.1869 TD
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[(the)-386.6(f)3.5(unctional)-379.1(l)-15.2(i)10.3(m)1.6(itations)-383.5(at)-15.2(t)10.3(r)3.5(ibuted)-382.3(to)-382.3(just)-384.6(the)-386.6(T)2.6(BI.)-383(T)-2.8(his)]TJ
0 -1.1923 TD
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[(w)4(a)-1.5(s)-377.8(r)-1.7(efe)4(rre)3.9(d)-382(t).5(o)-376.6(b)2.8(y)-382(t).5(he)-380.8(TRACK-)3.8(TBI)-381(s)1.6(tudy,)-377.3(a)-1.5(nd)-382(her)3.8(eafter)]TJ
T*
-.0143 Tc
[(in)-262.2(this)-263.4(ar)4.4(ti)-14.3(c)14.6(l)1.1(e,)-262.9(as)-263.4(t)-14.3(h)13.4(e)-266.4()47.7()4.4(GOSE)-262(2)3.4(-ways)-263.4(i)1.1(nter)4.4(view)4.6(.)53.1()-266.6(T)-1.9(he)-266.4(low-)]TJ
0 -1.1869 TD
-.0147 Tc
[(est)-405.7(\()-1.5(worst\))-407.9(rating)-408.9(i).7(n)-408.9(a)4.1(ny)-408.9(sec)4.1(t)-14.7(i)10.8(o)3(n)-408.9(t).7(hat)-405.7(i)-14.7(n)13(d)3(icated)-408.9(a)-407.7(c)-1.3(hange)]TJ
0 -1.1923 TD
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[(fro)-3.7(m)-459.7(p)-3.7(r)-2.7(e-inj)-15.9(u)11.8(ry)-464.3(fu)-3.7(nction)-469.7(d)1.8(eterm)-4.5(i)-.5(ned)-464.3(t)-.5(he)-468.6(ov)-3.7(erall)-466.5(G)3(OSE)-3.5(-)]TJ
T*
-.0162 Tc
[(Al)-16.2(l)-413.5(r)-3(at)-16.2(i)9.3(ng.)-427.4(T)-3.8(h)1.5(e)-425.5(o)-4(verall)-428.9(GOSE)-3.8(T)-3.8(BI)-425.7(ratin)-4(g)-421.3(w)-2.7(as)-427.9(based)-426.7(o)1.5(n)]TJ
0 -1.1869 TD
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[(the)-343.3(l).1(owest)-335.9(\()-2.1(worst\))-338.1(rating)-339.1(i).1(n)-339.1(a)-1.9(ny)-339.1(secti)-15.3(o)12.4(n)-339.1(a)-1.9(ttri)-15.3(b)12.4(uted)-339.1(to)-339.1(only)]TJ
0 -1.1923 TD
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[(the)-488.8(T)3.3(BI.)-485.3(T)3.3(he)-483.4(decision)-484.6(to)-484.6(obtain)-484.6(t).9(he)-483.4(two)-484.6(G)4.4(OSE)-484.4(s)2(cor)4.2(e)-1.1(s)]TJ
0 -1.1869 TD
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[(wa)-4.3(s)-266.8(m)-6.3(ad)-5.5(e)-264.4(t)-2.3(o)-265.6(a)-4.3(llo)-5.5(w)-264.4(c)-4.3(om)-6.3(pa)-4.3(ri)-17.7(s)8.8(o)0(n)-265.6(o)-5.5(f)-264.6(t)-2.3(h)-5.5(e)-264.4(T)-5.3(R)-2.1(AC)-7.5(K-)-4.5(TB)-7.5(I)-264.6(r)-4.5(es)-6.7(ults)]TJ
0 -1.1923 TD
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[(wi)-16.2(t)9.3(h)-296.6(those)-300.8(f)-3(rom)-297.4(t)-.8(he)-300.8(longitudi)]TJ
11.5004 0 TD
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[(nal,)-296(observational)-297.5(C).7(ENTER-)]TJ
-11.5004 -1.1923 TD
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[(TBI)-301.4(s)-5.6(tud)-4.4(y)1.1(,)]TJ
7.8454 0 0 6.9729 354.6707 552.4156 Tm
-.0158 Tc
(23)Tj
10.4607 0 0 10.4607 365.329 547.7668 Tm
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[(whi)-15.1(c)13.8(h)-300.9(acqui)-15.1(r)13.6(e)-1.7(d)-300.9(o)2.6(nly)-295.5(GOSE-All)-297.7(r)-1.9(atings.)]TJ
/F3 1 Tf
-5.2082 -2.2817 TD
0 Tc
[(Patient/Surrogate)-294.7(interviews.)]TJ
/F8 1 Tf
13.0829 0 TD
[(An)-288.6(interview)-292.9(completed)]TJ
-13.0829 -1.1923 TD
[(at)-290.9(the)-294.9(time)-291.1(of)-294.3(enrollment,)-292.9(by)-289.9(the)-294.9(participant)-292.4(or)-288.9(their)-293.3(sur-)]TJ
0 -1.1869 TD
[(rogate,)-325.7(collected)-330.7(pre-injury)-322.2(information,)-329.6(including)-323.4(work)]TJ
0 -1.1923 TD
[(and)-298.1(school)-297.3(status)-300.7(and)-298.1(living)-301.8(situation.)]TJ
1.046 -1.1923 TD
[(At)-258.3(each)-256.4(follow-up)-254.2(period,)-251.1(participants,)-258.9(or)-256.3(a)-252.1(close)-259.6(fam-)]TJ
-1.046 -1.1869 TD
[(ily)-211.6(member)-217.5(in)-216.2(the)-213.6(case)-219.6(of)-213(the)-219(more)-215.2(severely)-215.2(injured,)-213.9(com-)]TJ
0 -1.1923 TD
[(pleted)-335.1(a)-333.4(post-injury)-337.3(follow-up)-330(interview.)-335.6(This)-333.6(interview)]TJ
T*
[(documented)-256.4(current)-264.4(status)-262.8(and)-260.2(the)-262.4(reason)-260.4(for)-264.8(any)-260.2(change)]TJ
0 -1.1869 TD
[(from)-334.6(the)-332.8(pre-injury)-333.1(situation.)-337(Both)-329.2(interviews)-336.1(were)-336.6(cre-)]TJ
0 -1.1923 TD
[(ated)-335.7(by)-338.6(the)-338.3(TRACK-TBI)-335.4(outcome)-337.7(core)-337.9(leadership)-339.3(team)]TJ
T*
[(guided)-296.1(by)-300.7(NINDS)-299.5(TBI)-300.1(Common)-293.3(Data)-301.9(Elements.)]TJ
/F2 1 Tf
0 -2.4713 TD
[(Assessor)-296.3(training)]TJ
/F8 1 Tf
0 -1.2032 TD
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[(Before)-238.5(opening)-239.7(enro)4.2(llment,)-240.4(o)-1.2(u)4.2(t)-3.4(come)-238.5(assessors)-240.9(fro)4.2(m)-240.5(t)-3.4(h)4.2(e)-243.9(rst)]TJ
0 -1.1923 TD
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[(11)-461.7(sites)-462.9(r)0(eceived)-461.7(i)2.2(nstruction)-461.7(in)-461.7(the)-465.9(a).2(dministration)-461.7(o)-1(f)-460.7(t)-3.2(he)]TJ
0 -1.1869 TD
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[(GOSE)-153.6(a)-.8(nd)-153.8(othe)-6.3(r)-147.3(outcome)-152.6(measures)-149.5(a)-6.2(t)-145.2(a)-152.6(2)-2(-da)-6.3(y)-148.4(in-person)-148.4(t)-4.2(rain-)]TJ
0 -1.1923 TD
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[(ing)-244.7(s)-2(ession)-244.7(co)4.6(nvened)-244.7(b)-.8(y)-244.7(T)-.6(RACK-TBIs)-245.9(outcome)-248.9(core)-243.5(lead-)]TJ
T*
-.0232 Tc
[(ersh)5.3(ip)-444.5(and)-444.5(c)1.1(o)5.3(nducted)-444.5(b)-.1(y)-444.5(a)1.1(ppo)5.3(inted)-444.5(t)3.1(eam)-445.4(m)4.5(embers.)-445.2(N)1.1(in)5.3(e)]TJ
0 -1.1869 TD
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[(months)-262.1(into)-260.9(data)-265.1(collectio)4.7(n,)-261.6(training)-260.9(was)-267.5(co)4.7(nducted)-266.3(b)4.7(y)-260.9(t)-2.9(ele-)]TJ
0 -1.1923 TD
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[(phone)-439.4(to)-440.6(introduce)-439.4(t)-3.8(he)-444.8(GOSE)-440.4(2)-1.6(-ways)-436.4(a)-5.9(ssessment.)-441.3(When)]TJ
T*
-.0238 Tc
[(the)-324.7(s)3.5(even)-325.9(n)4.7(e)-5(w)-319.3(s)-1.9(ites)-321.7(were)-324.7(a).5(dded)4.7(,)-326.6(ano)4.7(t)-2.9(her)-319.5(i)-2.9(n)4.7(-).3(person)-320.5(training)]TJ
0 -1.1869 TD
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[(se)-5.5(ssion)-272.2(was)-273.4(held)-272.2(for)-276.6(a)0(ssessors)-273.4(from)-273(a)0(ll)-269(18)-272.2(sites.)-278.3(The)-276.4(s)3(ec)-5.5(ond)]TJ
0 -1.1923 TD
[(se)-5.5(ssion)-196.3(was)-197.5(designed)-196.3(t)2(o)-196.3(a)0(ddress)-197.5(p)-1.2(roblem)-191.7(a)-5.5(r)-.2(eas)-192.1(in)-196.3(administer-)]TJ
0 -1.1869 TD
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[(ing)-353.7(a)-.2(nd)-353.7(scoring)-353.7(t)1.8(he)-357.9(GOSE)-358.9(t)1.8(hat)-355.9(h)4(a)-5.7(d)-353.7(be)-5.7(en)-353.7(identi)-3.6(ed)-353.7(b)-1.4(y)-353.7(t)-3.6(he)]TJ
0 -1.1923 TD
[(TRACK-TBI)-195.5(O)-.2(utcomes)-197.7(C)-3.4(ore)-200.8(l)1.8(ea)-5.7(dership)-196.5(t)-3.6(eam.)-197.2(T)4.2(he)-200.8(Sta)-5.7(ndard)]TJ
T*
[(Operating)-570.6(P)-3.7(roc)-5.7(e)-.3(dures)-571.8(f)-.5(or)-569.6(Outcome)-569.4(A)-.3(sse)-5.8(s)2.7(sme)-5.8(n)3.9(t)-572.8(M)-1.3(anual)]TJ
0 -1.1869 TD
-.024 Tc
(\(SOP\),)Tj
7.8454 0 0 6.9729 337.9464 203.6976 Tm
-.0303 Tc
(24)Tj
10.4607 0 0 10.4607 349.8519 199.0488 Tm
-.0237 Tc
[(with)-428.8(specic)-433(guidance)-433(f).4(or)-433.2(the)-433(a).6(dministration)-434.2(o)-.6(f)]TJ
-3.7287 -1.1923 TD
-.0246 Tc
[(the)-244.2(GOSE)-245.2(b)3.9(a)-5.7(s)2.7(ed)-245.4(on)-245.4(ma)-5.8(terial)-242.2(codied)-245.4(i)1.7(n)-240(t)-3.7(he)-238.8(Wilson)-240(and)-245.4(c)-.3(ol-)]TJ
T*
-.024 Tc
[(leagues)-267.7(M)-.7(an)4.5(ual)-268.7(p)4.5(ublished)-266.5(c).3(oncurren)4.5(t)-3.1(ly,)]TJ
7.8454 0 0 6.9729 470.2109 178.7527 Tm
-.0375 Tc
(14)Tj
10.4607 0 0 10.4607 480.3022 174.1039 Tm
-.024 Tc
[(was)-267.7(poste)-5.2(d)-261.1(to)-266.5(the)]TJ
-16.1992 -1.1869 TD
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[(TRACK-TBI)-298.2(W)-4(eb)-299.2(site)-303.4(and)-299.2(p)4.3(rovided)-299.2(t)-3.3(o)-299.2(a).1(ssessors.)]TJ
1.046 -1.1923 TD
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[(All)-183.1(a)-.8(ssessors)-187.5(joining)-180.9(t)-4.2(he)-185.1(study)-180.9(a)-.8(t)-183.1(a)-.8(ny)-180.9(time)-185.1(were)-185.1(r)4.4(equire)4.6(d)-186.3(t)1.2(o)]TJ
-1.046 -1.1923 TD
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[(practi)-4.8(c)4(e)-435(a)-1.4(dminist)-4.8(e)-1.4(ri)-4.8(ng)-430.8(t)-4.8(h)2.8(e)-435(G)4(OS)-4.8(E)-430.6(w)-1.4(ith)-430.8(mock)-430.8(participant)-4.8(s)1.6(.)]TJ
0 -1.1869 TD
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[(TRACK-TBI)-206.9(o)3.5(utcome)-206.7(assessors)-203.6(r)4.5(anged)-202.5(i)-4.1(n)-202.5(l)1.3(eve)4.7(l)-204.7(of)-201.4(education)]TJ
0 -1.1923 TD
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[(fr)4.7(om)-278.9(a)-282.4(b)3.7(achelors)-279.3(degree)-282.3(to)-278.1(PhD)-276.9(o)-1.7(r)-277.1(M)-1.5(D,)-278.8(with)-283.5(a)-276.9(B)-3.7(A)-276.9(o)-1.7(r)-277.1(M)-1.5(A)]TJ
T*
-.0254 Tc
[(being)-197.4(t)-4.5(he)-201.7(most)-199.7(common.)-198.1(M)-2.1(any)-202.8(o)3.1(utcome)-201.7(assessors)-198.6(h)3.1(ad)-202.9(previ-)]TJ
0 -1.1869 TD
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[(o)14.6(u)9.2(s)-225.1(o)9.2(u)14.6(t)12.4(c)10.4(o)9.2(m)13.8(e)-228.1(e)10.4(v)9.2(a)15.8(l)7(u)14.6(a)10.4(t)12.4(i)7(o)14.6(n)-229.3(e)4.9(x)-1.7(perie)4.9(n)-1.7(ce)-233.5(as)-235.9(well)-236.9(a)5(s)-235.9(e)-.5(xper)4.8(i)-13.9(e)15(nc)5(e)-238.9(i)1.5(n)]TJ
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